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As previously discussed, RMECs are highly sensitive to ferroptosis under pathological conditions, as they poorly upregulate GPX4 and SLC7A11, while RPE cells resist ferroptosis via upregulating FTH1 and activating the Nrf2 antioxidant pathway (154)

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doi: 10.1242/dev.00966 184 ParkS-WVerhaegheCNguyenvuLTBarbeauREisleyCJNakagamiYet al

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Metabolism 49 : 225228

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